Chloramphenicol, also known as Chloromycetin, Chlornitromycin, or Levomycetin, is a broad-spectrum antibiotic. USP Grade Chloramphenicol is often used for bacterial selection in molecular biology applications at 10-20 μg/mL and as a selection agent for transformed cells containing chloramphenicol resistance genes.
Chloramphenicol is a broad-spectrum antibiotic that inhibits translation on the 50S ribosomal subunit at the peptidyltransferase step and prevents attachment of aminoacyl tRNA to the ribosome. It is usually bacteriostatic and effective against a wide range of gram-positive and gram-negative organisms. In addition, Chloramphenicol exhibits anti-rickettsial activity and is active against chlamydias of the psittacosis-lymphogranuloma group. Chloramphenicol acetyltransferase (CAT) catalyzes the acetylation of chloramphenicol, causing resistance to chloramphenicol. Chloramphenicol is often used for bacterial selection in molecular biology applications at 10-20 μg/mL and as a selection agent for transformed cells containing chloramphenicol resistance genes.
Features
Applications
Synonyms | Chloromycetin, Chlornitromycin, Levomycetin> |
CAS# | 56-75-7 |
Formula | C11H12Cl2N2O5 |
Molecular Weight | 323.13 |
Appearance | Crystalline powder |
Grade | USP |
Structure |
Components No. | Name | 60205ES08 | 60205ES25 | 60205ES60 |
60205 | Chloramphenicol, USP Grade | 5 g | 25 g | 100 g |
The product is shipped with ice packs and can be stored at 2℃~8℃ for 2 years.
[1] Li Z, Zhang L, Song Q, et al. Proteomics Analysis Reveals Bacterial Antibiotics Resistance Mechanism Mediated by ahslyA Against Enoxacin in Aeromonas hydrophila. Front Microbiol. 2021;12:699415. Published 2021 Jun 8. doi:10.3389/fmicb.2021.699415(IF:5.640)
[2] Xu R, Li D, Peng J, Fang J, Zhang L, Liu L. Cloning, expression and antioxidant activity of a novel collagen from Pelodiscus sinensis. World J Microbiol Biotechnol. 2016;32(6):100. doi:10.1007/s11274-016-2057-9(IF:1.532)
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