Ciprofloxacin hydrochloride

Details:

Product Description

Ciprofloxacin HCl, an analog of Nalidixic Acid, is a highly active fluoroquinoline antibiotic effective against a broad spectrum of bacteria and mycoplasma with few known resistant strains. Ciprofloxacin HCl functions by inhibiting DNA gyrase and topoisomerase IV, enzymes responsible for negative supercoiling of chromosomes and DNA strand separation, thus blocking initiation of bacterial replication. Ciprofloxacin HCl is effective at a low concentration (10 µg/mL) and can effectively eradicate mycoplasma in as little as 12 days. Ciprofloxacin HCl has been used as a plant fungicide. Ciprofloxacin HCl shows a broad spectrum of antibacterial activity against gram positive and gram negative bacteria.
Powder should be prepared in water or buffered media. To prepare a stock solution, add the appropriate amount of powder to distilled deionized water while mixing. Adding water directly to the powder could result in insoluble mixtures that cannot be filtered without losing potency. After ensuring that the mixture is completely solubilized, filter sterilize. If desired, the pH may be adjusted. 

Product Properties

Synonyms

CPX, Cetraxal, Ciloxan, Cipro, Bay-09867 hydrochloride

CAS#

93107-08-5

Formula

C17H18FN3O3·HCl

Molecular Weight

367.9

Appearance

powder

Structure

Shipping and Storage

The product is transported and stored at room temperature, with a period of validity of 1 year.

Cautions

1.For your safety and health, please wear lab coats and disposable gloves for operation.

2.For research use only.

Citations & References:

[1] Li Z, Zhang L, Song Q, et al. Proteomics Analysis Reveals Bacterial Antibiotics Resistance Mechanism Mediated by ahslyA Against Enoxacin in Aeromonas hydrophila. Front Microbiol. 2021;12:699415. Published 2021 Jun 8. doi:10.3389/fmicb.2021.699415(IF:5.640)

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