Neomycin Sulfate

Details:

Description

Neomycin sulfate from Yeasen is supplied in the form of white powder and is a USP-grade reagent with a solubility of about 200 mg/mL in water. It is an aminoglycoside antibiotic and can inhibit DNA degradation induced by DNase I.

Neomycin sulfate, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S and 50S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin sulfate inhibits PLC (Phospholipase C) via binding to inositol phospholipids. It also inhibits phosphatidylcholine-PLD activity and induces Ca2+ mobilization and PLA2 activation in human platelets. Neomycin sulfate inhibits DNA degradation induced by DNase I.

Features

  • High-quality raw materials, all antibiotic product raw materials are sourced from high-quality fixed suppliers
  • Standardized production, using factory mass production mode
  • Wide range of applications, which can be used in the fields of molecular biology and biochemical experimental research of tissue culture
  • The cooperation platform covers the whole
  • To ensure product quality stability, the difference between batches is controlled within 1%

Applications

  • It is used to screen prokaryotes with resistance gene (neo)
  • Used for sterilization in cell culture
  • Inhibit DNA degradation induced by DNase I

Specifications

Synonyms Neomycin Sulfate
CAS# 1405-10-3
Formula C23H46N6O13·3H2SO4
Molecular Weight 908.88
Appearance White powder
Grade USP
Potency (Anhydrous) ≥ 600 μg/mg
Solubility Soluble in water: ≥ 200 mg/mL
Structure

Components

Components No. Name 60207ES25 60207ES60
60207 Neomycin Sulfate 25 g 100 g

Shipping and Storage

The product is transported and stored at room temperature, with a period of validity of three years.

Citations & References:

[1] Wu R, Mei X, Ye Y, et al. Zn(II)-curcumin solid dispersion impairs hepatocellular carcinoma growth and enhances chemotherapy by modulating gut microbiota-mediated zinc homeostasis. Pharmacol Res. 2019;150:104454. doi:10.1016/j.phrs.2019.104454(IF:7.658)

[2] Qiu Y, Yu J, Li Y, et al. Depletion of gut microbiota induces skeletal muscle atrophy by FXR-FGF15/19 signalling. Ann Med. 2021;53(1):508-522. doi:10.1080/07853890.2021.1900593(IF:4.709)

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