Vancomycin hydrochlorid, is an amphoteric glycopeptide antibiotic that is effective only against Gram-positive bacteria. The mechanism of action is that it can inhibit the insertion of NAM-peptide and NAG-peptide at the end of d-alanyl alanine, affect their participation in the formation of peptidoglycan skeleton, block the normal formation of the cell wall, and finally lead to the inability of bacteria to survive. Vancomycin can also change the permeability of bacterial cell membranes and interfere with RNA synthesis.
This product comes from Streptomyces orientalis, and the recommended working concentration is 3 µg/mL.
Synonyms |
Vancomycin hydrochloride; Vancocine, Vansolin |
CAS# |
1404-93-9 |
Molecular Weight |
1485.67 g/mol |
Molecular Formular |
C66H76Cl3N9O24 |
Appearance |
White powder |
Potency, dry basis |
≥900 μg/mg |
Solubility |
Dissolve in water (50 mg/mL), filter and sterilize before use. |
Structure |
The product component is shipped with ice pack and can be stored at -20℃ for 2 years.
1) The storage solution after filtration is sub packed and stored at -20℃ to avoid repeated freezing and thawing. Autoclaving solution is not allowed.
2) The powder frozen at -20℃ should be returned to room temperature before use.
3) For your safety and health, please wear experimental clothes and disposable gloves.
4) This product is only used for scientific research and is not allowed to be used on people.
[1] Jin M, Kong L, Han Y, Zhang S. Gut microbiota enhances the chemosensitivity of hepatocellular carcinoma to 5-fluorouracil in vivo by increasing curcumin bioavailability. Phytother Res. 2021;35(10):5823-5837. doi:10.1002/ptr.7240(IF:5.882)
[2] Qiu Y, Yu J, Li Y, et al. Depletion of gut microbiota induces skeletal muscle atrophy by FXR-FGF15/19 signalling. Ann Med. 2021;53(1):508-522. doi:10.1080/07853890.2021.1900593(IF:4.709)
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